Retinal Arterial Macroaneurysm : 30504-PD / 101910

Introduction

Case

 

A 73 year old female presents with a history of waking with visual blurring in the left eye three days earlier.  Although it has improved mildly since then, she still complains of seeing poorly from the eye.  There is no history of eye pain, flashes, or floaters and she reports no problems with the right eye.  Her past medical history is significant for hypertension, hypothyroidism, and osteoporosis while her past ocular history is unremarkable.

 

On examination, best-corrected visual acuity is 20/20 and 20/80 in the right and left eyes, respectively.  Anterior segment exam is normal.  Posterior segment exam of the left eye is shown below:

 



What is the most likely diagnosis?

 

1.     Diabetic retinopathy

INCORRECT- Although proliferative diabetic retinopathy is a common source of vitreous hemorrhage, there is no known history of diabetes in the patient, and nor is there signs of diabetic retinopathy present.

 

2.     Age-related macular degeneration

INCORRECT- Neovascular age-related macular degeneration can occasionally cause a vitreous hemorrhage.  However, this eccentrically located lesion is not typical of ARMD.

 

3.     Posterior vitreous detachment

Posterior vitreous detachment is an age-related shrinkage of the vitreous humour that can often cause vitreous hemorrhage when associated with a retinal tear or avulsion of a small papillary vessel.  The absence of preceding symptoms of flashes/floaters, as well as the retinal appearance in the fundus photo make this less likely.

 

4.     Retinal arterial macroaneurysm

CORRECT

Retinal arterial macroaneurysms (RAMs) are acquired dilatations of the retinal vasculature that are often associated with longstanding hypertension.  They are usually asymptomatic unless they develop significant leakage, in which case they cause visual blurring related to retinal haemorrhage, exudation, and/or edema.  Breakthrough vitreous haemorrhage can worsen the visual effects.    They are most commonly seen in the elderly (6th-8th decade) and have a slight female preponderance.1  The average age of onset 66.1-73.7.2 3